Quintara offers custom LNP formulation services to support the identification of high-efficiency, low-toxicity, and stable delivery systems. Our platform delivers comprehensive support for preclinical in vitro and in vivo studies, accelerating the development of innovative nucleic acid therapeutics.
High encapsulation efficiency
Reduced immunogenicity and toxicity
High delivery efficiency of mRNA
Validated commercial lipids
Recommended formulations with clear IP ownership
Client-supplied lipids
Preclinical grade: Batches up to 1000 mL
Seamless transition from preclinical research to clinical-stage development
Integrated solutions: From gene synthesis to delivery-ready mRNA-LNP products
Rapid turnaround: As fast as 4 weeks starting from CDS sequence
Fast turnaround
Highest level of accuracy
Free-to-operate plasmid backbone available
Validated UTR sequences
Stable Poly (A) tail
dsRNA reduced synthesis options
Non-infringing cap analogs and enzyme options
Purification options for various applications
Load from 0.5 mg to 100 mg of mRNA
Multiple lipid and formulation options
High encapsulation efficiency
Comprehensive testing panels
Additional testing options available
Standard Report of Analysis (RoA) provided
Research Grade | Preclinical Grade | |
Payload* | mRNA, saRNA | mRNA, saRNA |
Scale | 0.5 - 5mg | 10 -100 mg |
| Turnaround Time | 5-7 Business days | 7-9 Business days |
Deliverables | a)Individual cryotubes b)RoA | a)Individual cryotubes b)RoA |
* Additional payload types available upon request.
| Item | Method | Standard | Research Grade | Preclinical Grade |
| Appearance | Visual inspect | Clear and free of foreign particles |  | |
Concentration | RiboGreen | 0.05 – 0.4 mg/mL | | |
Encapsulation Efficiency | RiboGreen | > 85% | | |
Integrity | Capillary Electrophoresis | <4k nt: ≥75% >4k nt: report value |  | |
Particle Size | DLS | MC3-LNP 80-110 nm | | |
SM102-LNP 65-125 nm | ||||
LP01-LNP 65-125 nm | ||||
ALC0315-LNP 50-100 nm | ||||
Novel lipid: report value | ||||
PDI | DLS | Commercial lipids< 0.2 | | |
Zeta Potential | Zetasizer | ± 20.0 mV | | |
pH | pH Meter | 7.4 ± 0.5 | | |
| Endotoxin | Semiquantitative | <10EU/mg | | |
| Bioburden | Direct inoculation | No growth after 72 hrs | |  |
* ×: Not Included √: Included +: Optional
Quintara delivers fast, affordable NGS sequencing using advanced platforms.
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Precision and custom gene synthesis from Quintara Biosciences for your research needs.
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